Advanced Nanotechnologies for Gene- and Light-Based Therapies
At the Gene and Light NanoTherapies Lab (GLNT Lab), we design and evaluate nanoparticles and nanostructures for biomedical applications.
Our primary focus is on gene delivery and photonic stimulation to achieve photothermal and photomechanical effects, all with a strong emphasis on the development of novel therapeutic approaches.
Our mission
To harness the interaction between light, nanomaterials and biological systems to create new therapeutic possibilities. We combine fundamental research with nanotechnology, gene delivery and immunoengineering to develop precise strategies for controlling cellular functions and treating disease. Alongside our scientific work, we aim to foster a collaborative and nurturing environment where young researchers can develop independence, creativity and scientific ambition.
Our vision
We envision a future in which light can be used to manipulate biological processes with nanoscale precision, enabling safer and more effective therapies. By transforming nanomedicine from a passive delivery platform into a remotely controllable therapeutic technology, we aspire to advance personalised treatments for cancer and other diseases—and help bring them from the laboratory closer to patients.
Our main research lines include
Nanocarriers for Gene Therapy
We develop nanosystems —particularly for siRNA delivery— to treat diseases such as bladder cancer, diabetic wounds, and for the reprogramming of immune cells.
Photothermal & Photomechanical Effects
Using light-responsive nanomaterials and pulsed laser irradiation, we explore direct cytosolic delivery and light-triggered endosomal escape to enhance intracellular access of therapeutics.
Light-Triggered Immunogenic Cell Death
We’re expanding photoporation technology for whole tumor cell vaccines, with a focus on eliciting robust and targeted anticancer immune responses.
We believe in translating nanoscale innovations into real-world therapies through a combination of smart design, light-based modulation, and deep biological insight.
📍 Learn more about our RESEARCH
Advancing gene and light therapies through nanotechnology.
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